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Endothelium, Vascular

Name
Endothelium, Vascular
Namespace Keyword
MeSHAnatomy
Namespace
MeSH
Namespace Version
20170511
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/annotation/mesh-anatomy/mesh-anatomy-20170511.belanno

Sample Annotated Edges 5

a(CHEBI:"phosphatidyl-L-serine") decreases a(CHEBI:"nitric oxide") View Subject | View Object

In addition to cell-free Hb, membrane structural modification, externalization of phosphatidylserine,21 decreased cell membrane deformability,22,23 and increased endothelial adherence24 could alter vascular NO homeostasis. PubMed:27308950

Appears in Networks:
Annotations
MeSH
Endothelium, Vascular
Text Location
Introduction

a(HM:"stored erythrocytes") increases path(MESH:Hemolysis) View Subject | View Object

The stored RBCs had approximately 7 times the hemolysis of fresh blood. PubMed:27308950

Appears in Networks:
Annotations
MeSH
Endothelium, Vascular
Text Location
Introduction

a(HM:"stored erythrocytes") increases p(HGNC:HBB) View Subject | View Object

In the current observational study in patients undergoing multilevel spinal fusion surgery, we tested the hypothesis that moderate doses of stored RBC transfusions increase intravascular cell-free Hb and decrease NO availability in surgical patients. PubMed:27308950

Appears in Networks:
Annotations
MeSH
Endothelium, Vascular
Text Location
Introduction

a(HM:"stored erythrocytes") decreases a(CHEBI:"nitric oxide") View Subject | View Object

In the current observational study in patients undergoing multilevel spinal fusion surgery, we tested the hypothesis that moderate doses of stored RBC transfusions increase intravascular cell-free Hb and decrease NO availability in surgical patients. PubMed:27308950

Appears in Networks:
Annotations
MeSH
Endothelium, Vascular
Text Location
Introduction

bp(GO:"endothelial cell activation") decreases a(CHEBI:"nitric oxide") View Subject | View Object

In addition to cell-free Hb, membrane structural modification, externalization of phosphatidylserine,21 decreased cell membrane deformability,22,23 and increased endothelial adherence24 could alter vascular NO homeostasis. PubMed:27308950

Appears in Networks:
Annotations
MeSH
Endothelium, Vascular
Text Location
Introduction

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About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.