Innate immune system subgraph

Name: Innate immune system subgraph
Namespace Keyword: Subgraph
Namespace: NeuroMMSigDB
Namespace Version: 1.0.3
Namespace URL: https://arty.scai.fraunhofer.de/artifactory/bel/annotation/neurommsig/neurommsig-1.0.3.belanno

Sample Annotated Edges 2

a(CHEBI:"amyloid-beta") increases bp(GO:"innate immune response") View Subject | View Object

One of the canonical pathways of this innate immune response evoked by Abeta is the activation of the NOD-like receptor (NLR) family, pyrin domain containing 3 (NLRP3) inflammasome that became a focus of intense research PubMed:28019679

Appears in Networks:

Inflammasome activation and innate immunity in Alzheimer’s disease v1.0.2

Annotations

Confidence: High
NeuroMMSigDB: Amyloidogenic subgraph
NeuroMMSigDB: Innate immune system subgraph

bp(GO:"innate immune response") increases act(complex(GO:"NLRP3 inflammasome complex")) View Subject | View Object

Appears in Networks:

Inflammasome activation and innate immunity in Alzheimer’s disease v1.0.2

Annotations

Confidence: High
NeuroMMSigDB: Amyloidogenic subgraph
NeuroMMSigDB: Innate immune system subgraph

Showing 2 of 2 edges

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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.