p(NCBIGENE:140621)
However, embryos that recovered from heat shock in the presence of the CRF-R1 antagonist, antalarmin, experienced a greater increase in caspase-3 activity than embryos not given the antagonist PubMed:29807032
The endogenous response to heat shock was characterized by transient changes in caspase-3 activity and gene expression. PubMed:29807032
For embryos heat shocked at 6 hpf, the induction of caspase-3 activity was dependent on recovery time (interaction of main variables P=0.007), with a significant increase over controls at 7 h and 10 h recovery (Table 1). PubMed:29807032
CRF overexpression by mRNA microinjection reduced heat shock-induced caspase-3 activity by approximately 2-fold relative to control-injected embryos PubMed:29807032
The endogenous response to heat shock was characterized by transient changes in caspase-3 activity and gene expression. PubMed:29807032
BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.
If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.