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complex(p(HGNC:NFKB1), p(HGNC:RELA), p(HGNC:SYP))

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Components

Appears in Networks 1

Nuclear Factor Kappa-light-chain-enhancer of Activated B Cells (NF-κB) - a Friend, a Foe, or a Bystander - in the Neurodegenerative Cascade and Pathogenesis of Alzheimer's Disease v1.0.0

In-Edges 1

p(HGNC:SYP) increases complex(p(HGNC:NFKB1), p(HGNC:RELA), p(HGNC:SYP)) View Subject | View Object

Multiple studies have demonstrated the presence of NF-κB in the synapses and synaptosomal preparations [25, 35, 39] and the presynaptic protein synaptophysin has been shown to co-localize with the p65 and p50 subunits of NF- κB in synaptosomal preparations [25, 35, 39], also been observed in the dendritic spines of the post-synaptic densities of the synaptosomes isolated from the hippocampus and the cerebral cortex PubMed:28745240

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Annotations
MeSH
Alzheimer Disease

Out-Edges 3

complex(p(HGNC:NFKB1), p(HGNC:RELA), p(HGNC:SYP)) hasComponent p(HGNC:NFKB1) View Subject | View Object

Appears in Networks:

complex(p(HGNC:NFKB1), p(HGNC:RELA), p(HGNC:SYP)) hasComponent p(HGNC:RELA) View Subject | View Object

Appears in Networks:

complex(p(HGNC:NFKB1), p(HGNC:RELA), p(HGNC:SYP)) hasComponent p(HGNC:SYP) View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.