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path(HP:"Hyperintensity of cerebral white matter on MRI")

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Entity

Name
Hyperintensity of cerebral white matter on MRI
Namespace
HP
Namespace Version
2017-10-05
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/namespace/hp/hp-20171108.belns

Appears in Networks 1

Tau protein aggregation is associated with cellular senescence in the brain v1.0.0

In-Edges 2

composite(a(CHEBI:"dasatinib (anhydrous)"), a(CHEBI:quercetin)) decreases path(HP:"Hyperintensity of cerebral white matter on MRI") View Subject | View Object

However, tauNFT-Mapt0/0 mice treated with DQ did not display WMH volumes statistically different than control mice (P = 0.2458; Figure S5b, c) PubMed:30126037

Appears in Networks:
Annotations
Confidence
High
MeSH
Neurons

path(MESH:"Cerebral Small Vessel Diseases") increases path(HP:"Hyperintensity of cerebral white matter on MRI") View Subject | View Object

WMH is driven by cerebral small vessel disease, which causes chronic ischemia and increased risk of cognitive decline and dementia (reviewed, (Prins & Scheltens, 2015)) PubMed:30126037

Appears in Networks:
Annotations
Confidence
High
MeSH
Neurons

Out-Edges 0

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.