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Appears in Networks 2

In-Edges 3

bp(MESH:Aging) regulates p(MGI:Capn1) View Subject | View Object

Cpn-1 (calpain-1) and Ppp3cc (calcineurin, Nixon et al., 1994; Rozkalne et al., 2011; Furman and Norris, 2014), as well as a Ca2􏰅 release-activated Ca2􏰅 channel (ORAI1) were altered by aging and restored by FKBP1b treatment (Table 3). PubMed:29255009

p(MGI:Fkbp1b) regulates p(MGI:Capn1) View Subject | View Object

Cpn-1 (calpain-1) and Ppp3cc (calcineurin, Nixon et al., 1994; Rozkalne et al., 2011; Furman and Norris, 2014), as well as a Ca2􏰅 release-activated Ca2􏰅 channel (ORAI1) were altered by aging and restored by FKBP1b treatment (Table 3). PubMed:29255009

p(HBP:"APOE e4") increases p(MGI:Capn1) View Subject | View Object

The levels of CDK5, its regulatory subunits (p35 and p25) and calpain (including calpain1 and calpain2), but not GSK3ß, were significantly increased in E4FAD mice compared to E3FAD mice. PubMed:27087442

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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.