Cerebral Amyloid Angiopathy, Familial

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name: Cerebral Amyloid Angiopathy, Familial
Namespace: mesh
Namespace Version: 20180828
Namespace URL: https://raw.githubusercontent.com/pharmacome/terminology/1b20f0637c395f8aa89c2e2e342d7b704062c242/external/mesh-names.belns

Appears in Networks 2

Amyloid Precursor Protein Trafficking, Processing, and Function v1.0.0

Amyloid Precursor Protein Trafficking, Processing, and Function by Thinakaran, et al., 2008

Tau oligomers-Cytotoxicity, propagation, and mitochondrial damage v1.0.0

Tau oligomers-Cytotoxicity, propagation, and mitochondrial damage from Shafiei et al., 2017

In-Edges 2

p(HGNC:APP, var("?")) increases path(MESH:"Cerebral Amyloid Angiopathy, Familial") View Subject | View Object

More than 25 mutations in APP have been identified that are causative of the hereditary form of familial AD and a related condition of hereditary cerebral amyloid angiopathy. PubMed:18650430

Appears in Networks:

Amyloid Precursor Protein Trafficking, Processing, and Function v1.0.0

Annotations

Confidence: Medium

a(MESH:"Heparan Sulfate Proteoglycans") association path(MESH:"Cerebral Amyloid Angiopathy, Familial") View Subject | View Object

HSPGs are ubiquitously expressed in many cell types including neurons, and have been previously associated with dense core plaques, cerebrovascular amyloid, and NFT formation (van Horssen et al., 2001) PubMed:28420982

Appears in Networks:

Tau oligomers-Cytotoxicity, propagation, and mitochondrial damage v1.0.0

Annotations

MeSH: Extracellular Space
Confidence: High
MeSH: Exosomes
MeSH: Alzheimer Disease

Out-Edges 1

path(MESH:"Cerebral Amyloid Angiopathy, Familial") association a(MESH:"Heparan Sulfate Proteoglycans") View Subject | View Object

Appears in Networks:

Tau oligomers-Cytotoxicity, propagation, and mitochondrial damage v1.0.0

Annotations

MeSH: Extracellular Space
Confidence: High
MeSH: Exosomes
MeSH: Alzheimer Disease

About

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.