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p(MGI:Il17a)

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Entity

Name
Il17a
Namespace
mgi
Namespace Version
20181021
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/f2f993e599694ab5ce989cc39d789a499f75db99/external/mgi-names.belns

Appears in Networks 1

Amelioration of Experimental Autoimmune Encephalomyelitis by Anatabine v1.0.0

In-Edges 3

a(CHEBI:Anatabine) decreases p(MGI:Il17a) View Subject | View Object

However, anatabine significantly suppressed the production of IL-1b, IL-6 and IL-17A in the serum of EAE mice (Fig. 2B) but did not significantly impact IFN-gamma and TNF-alpha PubMed:23383175

Appears in Networks:
Annotations
MeSH
Serum
MeSH
Encephalomyelitis

a(CHEBI:Anatabine) decreases p(MGI:Il17a) View Subject | View Object

However, a significant reduction in IL-17 was observed in the spleen of EAE anatabine treated mice compared to EAE placebo mice (Fig. 2C) PubMed:23383175

Appears in Networks:
Annotations
MeSH
Spleen
MeSH
Encephalomyelitis

path(MESH:Encephalomyelitis) positiveCorrelation p(MGI:Il17a) View Subject | View Object

We found that IL-1b, IFN-gamma, TNF-alpha, IL-6 and IL-17A were significantly elevated in the serum of EAE mice compared to control non-immunized mice PubMed:23383175

Appears in Networks:
Annotations
MeSH
Serum

Out-Edges 1

p(MGI:Il17a) positiveCorrelation path(MESH:Encephalomyelitis) View Subject | View Object

We found that IL-1b, IFN-gamma, TNF-alpha, IL-6 and IL-17A were significantly elevated in the serum of EAE mice compared to control non-immunized mice PubMed:23383175

Appears in Networks:
Annotations
MeSH
Serum

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.