1. Catalog
  2. Nodes
  3. a(MESH:"Fetal Hemoglobin")

a(MESH:"Fetal Hemoglobin")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Fetal Hemoglobin
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 2

p(HGNC:HP) negativeCorrelation a(MESH:"Fetal Hemoglobin") View Subject | View Object

A negative correlation was found, i.e. an increased plasma cell-free HbF concentration was associated with a decreased plasma Hp concentration, when including all individuals, controls and women with PE (r = -0.335, p-value<0.0001, n = 145)(Fig 1A). PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Plasma
MeSH
Pre-Eclampsia
Text Location
Results

path(MESH:"Pre-Eclampsia") positiveCorrelation a(MESH:"Fetal Hemoglobin") View Subject | View Object

A 4-fold increase of the HbF concentration was seen in the PE patients (p-value 0.01) as compared to the controls. PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Placenta
MeSH
Pre-Eclampsia
Text Location
Results

Out-Edges 3

a(MESH:"Fetal Hemoglobin") increases a(HM:"Oxidative damage") View Subject | View Object

It was hypothesized that through the generation of reactive oxygen species (ROS), Hb induces oxidative damage to the placenta and a subsequent leakage over the blood-placental barrier [12]. PubMed:26368565

Appears in Networks:
Annotations
MeSH
Placenta
Text Location
Introduction

a(MESH:"Fetal Hemoglobin") positiveCorrelation path(MESH:"Pre-Eclampsia") View Subject | View Object

A 4-fold increase of the HbF concentration was seen in the PE patients (p-value 0.01) as compared to the controls. PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Placenta
MeSH
Pre-Eclampsia
Text Location
Results

a(MESH:"Fetal Hemoglobin") negativeCorrelation p(HGNC:HP) View Subject | View Object

A negative correlation was found, i.e. an increased plasma cell-free HbF concentration was associated with a decreased plasma Hp concentration, when including all individuals, controls and women with PE (r = -0.335, p-value<0.0001, n = 145)(Fig 1A). PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Plasma
MeSH
Pre-Eclampsia
Text Location
Results

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.