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path(MESH:"Pre-Eclampsia")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Pre-Eclampsia
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 10

a(CHEBI:heme) positiveCorrelation path(MESH:"Pre-Eclampsia") View Subject | View Object

In line with previously published studies [13,14] the extravascular heme- and radical scavenger A1M was significantly increased in plasma of women with PE. PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Plasma
MeSH
Pre-Eclampsia
Text Location
Discussion

a(MESH:"Fetal Hemoglobin") positiveCorrelation path(MESH:"Pre-Eclampsia") View Subject | View Object

A 4-fold increase of the HbF concentration was seen in the PE patients (p-value 0.01) as compared to the controls. PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Placenta
MeSH
Pre-Eclampsia
Text Location
Results

a(MESH:"haptoglobin-hemoglobin complex") positiveCorrelation path(MESH:"Pre-Eclampsia") View Subject | View Object

A statistically significant increase in the mean Hp-HbF concentration was observed for women with PE as compared to controls (p-value 0.018). PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Placenta
MeSH
Pre-Eclampsia
Text Location
Results

p(HGNC:HPX) negativeCorrelation path(MESH:"Pre-Eclampsia") View Subject | View Object

Analysis of the intravascular heme-scavenger protein Hpx showed a statistically significant decrease in plasma Hpx concentration of women with PE (p-value<0.0001) as compared to the controls (Table 3). PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Plasma
MeSH
Pre-Eclampsia
Text Location
Results

p(HGNC:CD163) positiveCorrelation path(MESH:"Pre-Eclampsia") View Subject | View Object

Soluble, shedded CD163, the macrophage receptor mediating elimination of the Hp-Hb complex, was analyzed in plasma [40–42]. The analysis showed a small but not statistically significant (p-value 0.37) increase in the PE group as compared to the controls (Table 3). PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Plasma
MeSH
Pre-Eclampsia
Text Location
Results

p(HGNC:HP) negativeCorrelation path(MESH:"Pre-Eclampsia") View Subject | View Object

Analysis of the Hp concentration in plasma showed a statistically significant decrease in Hp concentration in plasma samples of women with PE as compared to controls (pvalue< 0.0001). PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Plasma
MeSH
Pre-Eclampsia
Text Location
Results

p(HGNC:AMBP) positiveCorrelation path(MESH:"Pre-Eclampsia") View Subject | View Object

Analysis of plasma levels of the heme- and radical scavenger A1M showed a statistically significant increase of plasma A1M concentration in women with PE (p-value 0.035) as compared to controls (Table 3). PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Plasma
MeSH
Pre-Eclampsia
Text Location
Results

p(HGNC:AMBP) positiveCorrelation path(MESH:"Pre-Eclampsia") View Subject | View Object

In line with previously published studies [13,14] the extravascular heme- and radical scavenger A1M was significantly increased in plasma of women with PE. PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Plasma
MeSH
Pre-Eclampsia
Text Location
Discussion

path(MESH:Hypertension) positiveCorrelation path(MESH:"Pre-Eclampsia") View Subject | View Object

The classical findings that define PE are hypertension and proteinuria appearing after 20 weeks of gestation. PubMed:26368565

Appears in Networks:
Annotations
Text Location
Introduction

path(MESH:Proteinuria) positiveCorrelation path(MESH:"Pre-Eclampsia") View Subject | View Object

The classical findings that define PE are hypertension and proteinuria appearing after 20 weeks of gestation. PubMed:26368565

Appears in Networks:
Annotations
Text Location
Introduction

Out-Edges 10

path(MESH:"Pre-Eclampsia") positiveCorrelation path(MESH:Proteinuria) View Subject | View Object

The classical findings that define PE are hypertension and proteinuria appearing after 20 weeks of gestation. PubMed:26368565

Appears in Networks:
Annotations
Text Location
Introduction

path(MESH:"Pre-Eclampsia") positiveCorrelation path(MESH:Hypertension) View Subject | View Object

The classical findings that define PE are hypertension and proteinuria appearing after 20 weeks of gestation. PubMed:26368565

Appears in Networks:
Annotations
Text Location
Introduction

path(MESH:"Pre-Eclampsia") positiveCorrelation a(MESH:"Fetal Hemoglobin") View Subject | View Object

A 4-fold increase of the HbF concentration was seen in the PE patients (p-value 0.01) as compared to the controls. PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Placenta
MeSH
Pre-Eclampsia
Text Location
Results

path(MESH:"Pre-Eclampsia") positiveCorrelation a(MESH:"haptoglobin-hemoglobin complex") View Subject | View Object

A statistically significant increase in the mean Hp-HbF concentration was observed for women with PE as compared to controls (p-value 0.018). PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Placenta
MeSH
Pre-Eclampsia
Text Location
Results

path(MESH:"Pre-Eclampsia") negativeCorrelation p(HGNC:HP) View Subject | View Object

Analysis of the Hp concentration in plasma showed a statistically significant decrease in Hp concentration in plasma samples of women with PE as compared to controls (pvalue< 0.0001). PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Plasma
MeSH
Pre-Eclampsia
Text Location
Results

path(MESH:"Pre-Eclampsia") positiveCorrelation p(HGNC:CD163) View Subject | View Object

Soluble, shedded CD163, the macrophage receptor mediating elimination of the Hp-Hb complex, was analyzed in plasma [40–42]. The analysis showed a small but not statistically significant (p-value 0.37) increase in the PE group as compared to the controls (Table 3). PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Plasma
MeSH
Pre-Eclampsia
Text Location
Results

path(MESH:"Pre-Eclampsia") negativeCorrelation p(HGNC:HPX) View Subject | View Object

Analysis of the intravascular heme-scavenger protein Hpx showed a statistically significant decrease in plasma Hpx concentration of women with PE (p-value<0.0001) as compared to the controls (Table 3). PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Plasma
MeSH
Pre-Eclampsia
Text Location
Results

path(MESH:"Pre-Eclampsia") positiveCorrelation p(HGNC:AMBP) View Subject | View Object

Analysis of plasma levels of the heme- and radical scavenger A1M showed a statistically significant increase of plasma A1M concentration in women with PE (p-value 0.035) as compared to controls (Table 3). PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Plasma
MeSH
Pre-Eclampsia
Text Location
Results

path(MESH:"Pre-Eclampsia") positiveCorrelation p(HGNC:AMBP) View Subject | View Object

In line with previously published studies [13,14] the extravascular heme- and radical scavenger A1M was significantly increased in plasma of women with PE. PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Plasma
MeSH
Pre-Eclampsia
Text Location
Discussion

path(MESH:"Pre-Eclampsia") positiveCorrelation a(CHEBI:heme) View Subject | View Object

In line with previously published studies [13,14] the extravascular heme- and radical scavenger A1M was significantly increased in plasma of women with PE. PubMed:26368565

Appears in Networks:
Annotations
Cell Ontology (CL)
hepatocyte
MeSH
Plasma
MeSH
Pre-Eclampsia
Text Location
Discussion

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.