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a(HBP:"Tau dimers")

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Entity

Name
Tau dimers
Namespace
HBP
Namespace Version
20181128
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/7e4be528f12abd28be768b62402fba6e083eaf9e/export/hbp-names.belns

Appears in Networks 1

Pseudophosphorylation of tau at S422 enhances SDS-stable dimer formation and impairs both anterograde and retrograde fast axonal transport. v1.0.0

In-Edges 2

composite(a(HBP:"Tau aggregates"), p(HGNC:MAPT)) increases a(HBP:"Tau dimers") View Subject | View Object

In contrast, aggregation of either hT40 or S422E significantly increased the amount of SDS-stable dimers at 180 kDa (Fig. 4C; F(1,12) = 110.0; p b 0.0001), as compared to the levels of these species in the respective monomer samples. Furthermore, S422E aggregation significantly increased the amount of SDS-stable dimers compared to hT40 aggregation (p = 0.03). PubMed:27373205

Appears in Networks:

composite(a(HBP:"Tau aggregates"), p(HGNC:MAPT, var("p.S422E"))) increases a(HBP:"Tau dimers") View Subject | View Object

In contrast, aggregation of either hT40 or S422E significantly increased the amount of SDS-stable dimers at 180 kDa (Fig. 4C; F(1,12) = 110.0; p b 0.0001), as compared to the levels of these species in the respective monomer samples. Furthermore, S422E aggregation significantly increased the amount of SDS-stable dimers compared to hT40 aggregation (p = 0.03). PubMed:27373205

Appears in Networks:

Out-Edges 0

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.