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a(MESH:Thrombin)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Thrombin
Namespace
mesh
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/8ccfed235e418e4c8aa576f9a5ef0f838e794c7f/external/mesh-names.belns

Appears in Networks 2

Clearance of Amyloid Beta and Tau in Alzheimer’s Disease:from Mechanisms to Therapy v1.0.1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 2

bp(MESH:"Clot Retraction") positiveCorrelation a(MESH:Thrombin) View Subject | View Object

Thrombin, calcium ions, the integrin IIb 3, non-muscle myosin IIa, factor XIIIa crosslinking, and platelet count all promote one or more phases of the clot contraction process. PubMed:28458720

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Veins
MeSH
beta-Thalassemia
Text Location
Review

path(MESH:Hydrocephalus) positiveCorrelation a(MESH:Thrombin) View Subject | View Object

Our most recent study has shown that thrombin and thrombin receptor are involved in IVH-induced hydrocephalus. PubMed:24667910

Appears in Networks:
Annotations
MeSH
Ependyma
Text Location
Discussion

Out-Edges 3

a(MESH:Thrombin) increases deg(p(HGNC:MAPT)) View Subject | View Object

Human brain tau can be degraded by the proteases, such as cathepsin-D, amino peptidases, human high temperature requirement serine protease A1 (HTRA1), thrombin, caspases, and calpains (Chesser et al. 2013; Kenessey et al. 1997) PubMed:29626319

Appears in Networks:
Annotations
MeSH
Brain

a(MESH:Thrombin) positiveCorrelation path(MESH:Hydrocephalus) View Subject | View Object

Our most recent study has shown that thrombin and thrombin receptor are involved in IVH-induced hydrocephalus. PubMed:24667910

Appears in Networks:
Annotations
MeSH
Ependyma
Text Location
Discussion

a(MESH:Thrombin) positiveCorrelation bp(MESH:"Clot Retraction") View Subject | View Object

Thrombin, calcium ions, the integrin IIb 3, non-muscle myosin IIa, factor XIIIa crosslinking, and platelet count all promote one or more phases of the clot contraction process. PubMed:28458720

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Veins
MeSH
beta-Thalassemia
Text Location
Review

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.