1. Catalog
  2. Nodes
  3. p(HGNC:ATP6V0A1, pmod(NGlyco))

p(HGNC:ATP6V0A1, pmod(NGlyco))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
ATP6V0A1
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

The Ubiquitin–Proteasome System and the Autophagic–Lysosomal System in Alzheimer Disease v1.0.0

In-Edges 2

p(HGNC:ATP6V0A1) hasVariant p(HGNC:ATP6V0A1, pmod(NGlyco)) View Subject | View Object

Appears in Networks:

p(HGNC:PSEN1) increases p(HGNC:ATP6V0A1, pmod(NGlyco)) View Subject | View Object

In the absence of PS1, the V0a1 subunit of v-ATPase is not N-glycosylated in the ER and is degraded before sufficient amounts can be delivered to autolysosomes/lysosomes to support lysosomal acidification. PubMed:22908190

Appears in Networks:
Annotations
MeSH
Lysosomes

Out-Edges 1

p(HGNC:ATP6V0A1, pmod(NGlyco)) increases bp(GO:"pH reduction") View Subject | View Object

In the absence of PS1, the V0a1 subunit of v-ATPase is not N-glycosylated in the ER and is degraded before sufficient amounts can be delivered to autolysosomes/lysosomes to support lysosomal acidification. PubMed:22908190

Appears in Networks:
Annotations
MeSH
Lysosomes

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.