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a(HBP:HBP00075)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
HBP00075
Namespace
HBP
Namespace Version
20181029
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/785431732a26d6809b4162d98b95687d16404e63/export/hbp.belns

Appears in Networks 1

Amyloid β oligomers (AβOs) in Alzheimer’s disease v1.0.0

In-Edges 0

Out-Edges 3

a(HBP:HBP00075) decreases p(MGI:Adrb2) View Subject | View Object

LMW oligomers led to a decrease in the neuronal levels of β2ARs, activated brain microglia, and induced impaired hippocampal LTP in mice in vivo (Yang et al. 2017). PubMed:29196815

Appears in Networks:
Annotations
MeSH
Extracellular Space
Cell Ontology (CL)
neuron
Confidence
Medium

a(HBP:HBP00075) increases bp(GO:"microglial cell activation") View Subject | View Object

LMW oligomers led to a decrease in the neuronal levels of β2ARs, activated brain microglia, and induced impaired hippocampal LTP in mice in vivo (Yang et al. 2017). PubMed:29196815

Appears in Networks:
Annotations
MeSH
Extracellular Space
Confidence
Medium
MeSH
Brain

a(HBP:HBP00075) decreases bp(GO:"long-term synaptic potentiation") View Subject | View Object

LMW oligomers led to a decrease in the neuronal levels of β2ARs, activated brain microglia, and induced impaired hippocampal LTP in mice in vivo (Yang et al. 2017). PubMed:29196815

Appears in Networks:
Annotations
MeSH
Extracellular Space
Confidence
Medium
MeSH
Hippocampus

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.