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path(MESH:D008568)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
D008568
Namespace
mesh
Namespace Version
20180828
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/1b20f0637c395f8aa89c2e2e342d7b704062c242/external/mesh.belns

Appears in Networks 2

Interplay of neurotransmitters in Alzheimer's disease v1.0.0

Cholinergic system during the progression of Alzheimer’s disease: therapeutic implications v1.0.0

In-Edges 6

a(CHEBI:"glutamate(1-)") association path(MESH:D008568) View Subject | View Object

The capacity for thinking and remembering is derived from various input and output pathways between the hippocampus and the neocortex,9 and all such pathways rely on signaling mediated by the neurotransmitter glutamate. PubMed:16273023

Appears in Networks:

bp(MESH:D017774) association path(MESH:D008568) View Subject | View Object

It is believed that LTP, which can persist at a given synapse for periods ranging from hours to months, models the processes of learning and memory, and a number of studies have demonstrated a loss of LTP in animal models of Alzheimer's disease. PubMed:16273023

Appears in Networks:
Annotations
Cell Ontology (CL)
glial cell
MeSH
Frontal Lobe
MeSH
Temporal Lobe

a(MESH:D006624) association path(MESH:D008568) View Subject | View Object

The capacity for thinking and remembering is derived from various input and output pathways between the hippocampus and the neocortex,9 and all such pathways rely on signaling mediated by the neurotransmitter glutamate. PubMed:16273023

Appears in Networks:

a(MESH:D019579) association path(MESH:D008568) View Subject | View Object

The capacity for thinking and remembering is derived from various input and output pathways between the hippocampus and the neocortex,9 and all such pathways rely on signaling mediated by the neurotransmitter glutamate. PubMed:16273023

Appears in Networks:

a(MESH:D059329) association path(MESH:D008568) View Subject | View Object

Cholinergic neurons within the nucleus basalis (NB) and the septal diagonal band complex provide the major source of cholinergic innervation to the cerebral cortex and hippocampus, respectively, and play a key role in memory and attentional function [11–13]. PubMed:18986241

Appears in Networks:
Annotations
MeSH
Basal Nucleus of Meynert
MeSH
Cerebral Cortex
MeSH
Hippocampus

path(MESH:D000544) association path(MESH:D008568) View Subject | View Object

Alzheimer’s disease (AD) is a progressive and fatal neurodegenerative disorder manifested by cognitive and memory decline and progressive impairment of activities of daily living, as well as a variety of neuropsychiatric symptoms and behavioral dysfunctions. PubMed:18986241

Appears in Networks:

Out-Edges 6

path(MESH:D008568) association a(MESH:D006624) View Subject | View Object

The capacity for thinking and remembering is derived from various input and output pathways between the hippocampus and the neocortex,9 and all such pathways rely on signaling mediated by the neurotransmitter glutamate. PubMed:16273023

Appears in Networks:

path(MESH:D008568) association a(MESH:D019579) View Subject | View Object

The capacity for thinking and remembering is derived from various input and output pathways between the hippocampus and the neocortex,9 and all such pathways rely on signaling mediated by the neurotransmitter glutamate. PubMed:16273023

Appears in Networks:

path(MESH:D008568) association a(CHEBI:"glutamate(1-)") View Subject | View Object

The capacity for thinking and remembering is derived from various input and output pathways between the hippocampus and the neocortex,9 and all such pathways rely on signaling mediated by the neurotransmitter glutamate. PubMed:16273023

Appears in Networks:

path(MESH:D008568) association bp(MESH:D017774) View Subject | View Object

It is believed that LTP, which can persist at a given synapse for periods ranging from hours to months, models the processes of learning and memory, and a number of studies have demonstrated a loss of LTP in animal models of Alzheimer's disease. PubMed:16273023

Appears in Networks:
Annotations
Cell Ontology (CL)
glial cell
MeSH
Frontal Lobe
MeSH
Temporal Lobe

path(MESH:D008568) association path(MESH:D000544) View Subject | View Object

Alzheimer’s disease (AD) is a progressive and fatal neurodegenerative disorder manifested by cognitive and memory decline and progressive impairment of activities of daily living, as well as a variety of neuropsychiatric symptoms and behavioral dysfunctions. PubMed:18986241

Appears in Networks:

path(MESH:D008568) association a(MESH:D059329) View Subject | View Object

Cholinergic neurons within the nucleus basalis (NB) and the septal diagonal band complex provide the major source of cholinergic innervation to the cerebral cortex and hippocampus, respectively, and play a key role in memory and attentional function [11–13]. PubMed:18986241

Appears in Networks:
Annotations
MeSH
Basal Nucleus of Meynert
MeSH
Cerebral Cortex
MeSH
Hippocampus

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.