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bp(MESH:Hematocrit)

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Entity

Name
Hematocrit
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 3

a(CHEBI:"lead nitrate") decreases bp(MESH:Hematocrit) View Subject | View Object

Furthermore, the level of hematocrit (HCT) was also diminished by roughly 15% in Ko + Pb mice, compared to that in Wt + Pb mice (Table 1), and the mean corpuscular volume (MCV) in Ko + Pb mice was elevated by approximately 15% and 21%, compared to that in Ko − Pb mice and Wt + Pb mice, respectively (Table 1; P < 0.05). PubMed:25411909

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Annotations
MeSH
Serum
Text Location
Results

bp(MESH:"Blood Transfusion") increases bp(MESH:Hematocrit) View Subject | View Object

We calculated the loss of blood and extent of hemodilution during and after surgery based on the Hct levels for nontransfused patients (Table 1). Hct was significantly decreased (by approximately 20%, P = 0.0087) and hemodilution was significantly increased (P = 0.007) in these patients. PubMed:27308950

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MeSH
Plasma
Text Location
Results

path(MESH:Thrombosis) association bp(MESH:Hematocrit) View Subject | View Object

On the other hand, an abnormally high hematocrit is associated with thrombosis, and patients with polycythemia vera or taking erythropoietin are more susceptible to thrombosis and thromboembolism [4, 5]. PubMed:28458720

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Out-Edges 4

bp(MESH:Hematocrit) association path(MESH:Thrombosis) View Subject | View Object

On the other hand, an abnormally high hematocrit is associated with thrombosis, and patients with polycythemia vera or taking erythropoietin are more susceptible to thrombosis and thromboembolism [4, 5]. PubMed:28458720

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Text Location
Review

bp(MESH:Hematocrit) increases bp(MESH:"Blood Viscosity") View Subject | View Object

High hematocrit results in an increase in blood viscosity that impedes the blood flow [6, 7]. PubMed:28458720

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bp(MESH:Hematocrit) decreases bp(MESH:"Blood Flow Velocity") View Subject | View Object

High hematocrit results in an increase in blood viscosity that impedes the blood flow [6, 7]. PubMed:28458720

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bp(MESH:Hematocrit) increases bp(MESH:"Platelet Adhesiveness") View Subject | View Object

The hematocrit-related blood viscosity may have physical effects on the interaction between platelets and blood vessel surfaces.Under flow conditions, platelet adhesion increases greatly with hematocrit. PubMed:28458720

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About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.