1. Catalog
  2. Nodes
  3. a(HM:"erythrocyte-endothelium adhesion")

a(HM:"erythrocyte-endothelium adhesion")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
erythrocyte-endothelium adhesion
Namespace
HM
Namespace Version
None
Pattern
.*

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 8

a(CHEBI:"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine") decreases a(HM:"erythrocyte-endothelium adhesion") View Subject | View Object

TPEN also inhibited erythrocyte adhesion, but the effect at 20 mM was weaker compared to that in the HRG (100 mg/mL)- treatment group. PubMed:29544683

Appears in Networks:
Annotations
MeSH
Erythrocyte Membrane
MeSH
Sepsis
Text Location
Results

a(CHEBI:"zinc(2+)") increases a(HM:"erythrocyte-endothelium adhesion") View Subject | View Object

We found that a considerable number of erythrocytes were attached to the EA.hy926 cells after Zn2þ-stimulation (Fig. 4A). PubMed:29544683

Appears in Networks:
Annotations
MeSH
Erythrocyte Membrane
MeSH
Sepsis
Text Location
Results

a(CHEBI:"zinc(2+)") increases a(HM:"erythrocyte-endothelium adhesion") View Subject | View Object

In addition, we observed that Zn2þ induced the adhesion of erythrocytes to endothelial cells, and this effect was not inhibited by 100 mg/mL of HSA (Fig. 4), suggesting a specific interaction between erythrocytes and HRG. PubMed:29544683

Appears in Networks:
Annotations
MeSH
Erythrocyte Membrane
MeSH
Sepsis
Text Location
Discussion

p(HGNC:ALB) causesNoChange a(HM:"erythrocyte-endothelium adhesion") View Subject | View Object

HRG treatment significantly inhibited the attachment of erythrocytes to the vascular endothelial cell monolayer in a concentration dependent manner (Fig. 4A and B), while HSA did not affect the adhesion. PubMed:29544683

Appears in Networks:
Annotations
MeSH
Erythrocyte Membrane
MeSH
Sepsis
Text Location
Results

p(HGNC:HRG) decreases a(HM:"erythrocyte-endothelium adhesion") View Subject | View Object

HRG treatment significantly inhibited the attachment of erythrocytes to the vascular endothelial cell monolayer in a concentration dependent manner (Fig. 4A and B), while HSA did not affect the adhesion. PubMed:29544683

Appears in Networks:
Annotations
MeSH
Erythrocyte Membrane
MeSH
Sepsis
Text Location
Results

path(HP:"Diabetes mellitus") positiveCorrelation a(HM:"erythrocyte-endothelium adhesion") View Subject | View Object

The most common pathological states in which RBCs interact with the endothelium include sickle cell disease [39], malaria [40], and diabetes [41]. PubMed:28458720

Appears in Networks:
Annotations
MeSH
Veins
MeSH
Anemia, Sickle Cell
MeSH
beta-Thalassemia
Text Location
Review

path(MESH:"Anemia, Sickle Cell") positiveCorrelation a(HM:"erythrocyte-endothelium adhesion") View Subject | View Object

The most common pathological states in which RBCs interact with the endothelium include sickle cell disease [39], malaria [40], and diabetes [41]. PubMed:28458720

Appears in Networks:
Annotations
MeSH
Veins
MeSH
Anemia, Sickle Cell
MeSH
beta-Thalassemia
Text Location
Review

path(MESH:Malaria) positiveCorrelation a(HM:"erythrocyte-endothelium adhesion") View Subject | View Object

The most common pathological states in which RBCs interact with the endothelium include sickle cell disease [39], malaria [40], and diabetes [41]. PubMed:28458720

Appears in Networks:
Annotations
MeSH
Veins
MeSH
Anemia, Sickle Cell
MeSH
beta-Thalassemia
Text Location
Review

Out-Edges 3

a(HM:"erythrocyte-endothelium adhesion") positiveCorrelation path(MESH:Malaria) View Subject | View Object

The most common pathological states in which RBCs interact with the endothelium include sickle cell disease [39], malaria [40], and diabetes [41]. PubMed:28458720

Appears in Networks:
Annotations
MeSH
Veins
MeSH
Anemia, Sickle Cell
MeSH
beta-Thalassemia
Text Location
Review

a(HM:"erythrocyte-endothelium adhesion") positiveCorrelation path(MESH:"Anemia, Sickle Cell") View Subject | View Object

The most common pathological states in which RBCs interact with the endothelium include sickle cell disease [39], malaria [40], and diabetes [41]. PubMed:28458720

Appears in Networks:
Annotations
MeSH
Veins
MeSH
Anemia, Sickle Cell
MeSH
beta-Thalassemia
Text Location
Review

a(HM:"erythrocyte-endothelium adhesion") positiveCorrelation path(HP:"Diabetes mellitus") View Subject | View Object

The most common pathological states in which RBCs interact with the endothelium include sickle cell disease [39], malaria [40], and diabetes [41]. PubMed:28458720

Appears in Networks:
Annotations
MeSH
Veins
MeSH
Anemia, Sickle Cell
MeSH
beta-Thalassemia
Text Location
Review

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.