a(HM:"Erythrocytes, lysed") increases p(RGD:Hmox1)

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PubMed:24667910

The major findings of this study are (1) intraventricular injection of lysed RBCs but not packed RBCs resulted in hydrocephalus; (2) lysed RBCs upregulated brain HO-1 and ferritin levels; (3) intraventricular injection of iron also caused hydrocephalus; and (4) iron chelation with deferoxamine reduced lysed RBC-induced hydrocephalus.

Related Edges 8

• a(CHEBI:"desferrioxamine B") negativeCorrelation path(MESH:Hydrocephalus)
• a(CHEBI:"iron(2+)") positiveCorrelation path(MESH:Hydrocephalus)
• a(HM:"Erythrocytes, lysed") positiveCorrelation path(MESH:Hydrocephalus)
• a(HM:"Erythrocytes, lysed") positiveCorrelation p(PFAM:Ferritin)
• p(PFAM:Ferritin) positiveCorrelation a(HM:"Erythrocytes, lysed")
• path(MESH:Hydrocephalus) positiveCorrelation a(HM:"Erythrocytes, lysed")
• path(MESH:Hydrocephalus) positiveCorrelation a(CHEBI:"iron(2+)")
• path(MESH:Hydrocephalus) negativeCorrelation a(CHEBI:"desferrioxamine B")

MeSH

Ependyma

Text Location

Discussion

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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