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a(MESH:Mortality)

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Entity

Name
Mortality
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 7

a(HM:"stored erythrocytes") increases a(MESH:Mortality) View Subject | View Object

However, mortality significantly increased in mice resuscitated with stored RBCs (median survival 8 h, n = 9), with all mice dying within 20 h of PAK instillation (Fig 1C). PubMed:29522519

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a(MESH:"Blood Transfusion") positiveCorrelation a(MESH:Mortality) View Subject | View Object

After resuscitation with SRBCs, only 58% of mice survived for 48 hours (SRBC vs. FRBC, P<0.05). PubMed:27515135

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MeSH
Hemorrhage
Text Location
Results

complex(a(MESH:"Blood Transfusion"), p(MGI:Hp)) negativeCorrelation a(MESH:Mortality) View Subject | View Object

In contrast, all of the mice survived after SRBC-transfusion and treatment with hemopexin (SRBC+Hx vs. SRBC+Alb, P=0.018). Similarly the survival rate of mice resuscitated with SRBCs and co-infusion of haptoglobin was 96% (SRBC+Hp vs. SRBC+Alb, P=0.030). PubMed:27515135

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MeSH
Hemorrhage
Text Location
Results

complex(a(MESH:"Blood Transfusion"), p(MGI:Hpx)) negativeCorrelation a(MESH:Mortality) View Subject | View Object

In contrast, all of the mice survived after SRBC-transfusion and treatment with hemopexin (SRBC+Hx vs. SRBC+Alb, P=0.018). Similarly the survival rate of mice resuscitated with SRBCs and co-infusion of haptoglobin was 96% (SRBC+Hp vs. SRBC+Alb, P=0.030). PubMed:27515135

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MeSH
Hemorrhage
Text Location
Results

p(HGNC:HP) negativeCorrelation a(MESH:Mortality) View Subject | View Object

Increased circulating cell-free Hb, heme, and iron and decreased haptoglobin concentrations have been associated with morbidity and mortality in both animal models and patients.4,5 PubMed:29603246

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Introduction

path(MESH:Anemia) positiveCorrelation a(MESH:Mortality) View Subject | View Object

Moderate anemia is associated with increased mortality and morbidity, including acute kidney injury (AKI), in surgical patients. PubMed:29351418

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path(MESH:Anemia) positiveCorrelation a(MESH:Mortality) View Subject | View Object

Anemia has been associated with an increased risk of acute kidney injury (AKI) (17, 18, 20, 27, 28), stroke (17, 20, 27), myocardial events (6, 11, 20, 28, 47), and mortality (1, 2, 10, 11, 17, 20, 27, 28, 36, 45, 47) in patients undergoing surgery. PubMed:29351418

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Introduction

Out-Edges 6

a(MESH:Mortality) positiveCorrelation a(MESH:"Blood Transfusion") View Subject | View Object

After resuscitation with SRBCs, only 58% of mice survived for 48 hours (SRBC vs. FRBC, P<0.05). PubMed:27515135

Appears in Networks:
Annotations
MeSH
Hemorrhage
Text Location
Results

a(MESH:Mortality) negativeCorrelation complex(a(MESH:"Blood Transfusion"), p(MGI:Hpx)) View Subject | View Object

In contrast, all of the mice survived after SRBC-transfusion and treatment with hemopexin (SRBC+Hx vs. SRBC+Alb, P=0.018). Similarly the survival rate of mice resuscitated with SRBCs and co-infusion of haptoglobin was 96% (SRBC+Hp vs. SRBC+Alb, P=0.030). PubMed:27515135

Appears in Networks:
Annotations
MeSH
Hemorrhage
Text Location
Results

a(MESH:Mortality) negativeCorrelation complex(a(MESH:"Blood Transfusion"), p(MGI:Hp)) View Subject | View Object

In contrast, all of the mice survived after SRBC-transfusion and treatment with hemopexin (SRBC+Hx vs. SRBC+Alb, P=0.018). Similarly the survival rate of mice resuscitated with SRBCs and co-infusion of haptoglobin was 96% (SRBC+Hp vs. SRBC+Alb, P=0.030). PubMed:27515135

Appears in Networks:
Annotations
MeSH
Hemorrhage
Text Location
Results

a(MESH:Mortality) positiveCorrelation path(MESH:Anemia) View Subject | View Object

Moderate anemia is associated with increased mortality and morbidity, including acute kidney injury (AKI), in surgical patients. PubMed:29351418

Appears in Networks:
Annotations
Text Location
Abstract

a(MESH:Mortality) positiveCorrelation path(MESH:Anemia) View Subject | View Object

Anemia has been associated with an increased risk of acute kidney injury (AKI) (17, 18, 20, 27, 28), stroke (17, 20, 27), myocardial events (6, 11, 20, 28, 47), and mortality (1, 2, 10, 11, 17, 20, 27, 28, 36, 45, 47) in patients undergoing surgery. PubMed:29351418

Appears in Networks:
Annotations
Text Location
Introduction

a(MESH:Mortality) negativeCorrelation p(HGNC:HP) View Subject | View Object

Increased circulating cell-free Hb, heme, and iron and decreased haptoglobin concentrations have been associated with morbidity and mortality in both animal models and patients.4,5 PubMed:29603246

Appears in Networks:
Annotations
Text Location
Introduction

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.