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Appears in Networks 4

In-Edges 6

complex(HBP:"alpha-4 beta-2 nAChR") association path(MESH:Memory) View Subject | View Object

We found high correlation coefficients for four brain regions (right superior parietal lobule, left thalamus, right pos- terior subcortical region, and left posterior subcor- tical region) and two CERAD subtests (Word List Intrusions and Boston Naming Test), some of them were statistically significant. PubMed:24762290

path(MESH:"Parkinson Disease") decreases path(MESH:Memory) View Subject | View Object

Performance was impaired, compared with a normal population, in the subtests Figure Recall and Figure Saving. These both subtests examined non-verbal functions, namely non-verbal memory and visuoconstructive ability. PubMed:24762290

path(MESH:"Parkinson Disease") association path(MESH:Memory) View Subject | View Object

We found high correlation coefficients for four brain regions (right superior parietal lobule, left thalamus, right pos- terior subcortical region, and left posterior subcor- tical region) and two CERAD subtests (Word List Intrusions and Boston Naming Test), some of them were statistically significant. PubMed:24762290

p(MESH:"Receptors, Nicotinic") association path(MESH:Memory) View Subject | View Object

In the brain, nAChRs are widely expressed, both presyn- aptically and postsynaptically, and are involved in several functions including learning and memory, arousal, reward, motor control, and analgesia. nAChRs are also the target of nicotine, the main addictive agent delivered by cigarette smoke PubMed:28901280

p(HGNC:MAPT, loc(GO:"extracellular region")) decreases path(MESH:Memory) View Subject | View Object

Furthermore, extracellular oligomeric tau impairs memory and long-term potentiation (LTP) in mice PubMed:29238289

Out-Edges 3

path(MESH:Memory) association path(MESH:"Parkinson Disease") View Subject | View Object

We found high correlation coefficients for four brain regions (right superior parietal lobule, left thalamus, right pos- terior subcortical region, and left posterior subcor- tical region) and two CERAD subtests (Word List Intrusions and Boston Naming Test), some of them were statistically significant. PubMed:24762290

path(MESH:Memory) association complex(HBP:"alpha-4 beta-2 nAChR") View Subject | View Object

We found high correlation coefficients for four brain regions (right superior parietal lobule, left thalamus, right pos- terior subcortical region, and left posterior subcor- tical region) and two CERAD subtests (Word List Intrusions and Boston Naming Test), some of them were statistically significant. PubMed:24762290

path(MESH:Memory) association p(MESH:"Receptors, Nicotinic") View Subject | View Object

In the brain, nAChRs are widely expressed, both presyn- aptically and postsynaptically, and are involved in several functions including learning and memory, arousal, reward, motor control, and analgesia. nAChRs are also the target of nicotine, the main addictive agent delivered by cigarette smoke PubMed:28901280

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.