bp(GO:"cellular respiration")
Furthermore, different gene sets that are involved in the regulation of metabolite generation and processing, glycolysis and mitochondrial respiration and oxidative stress were also significantly altered in the hippocampus upon lymphatic ablation and performance of the behaviour test (Extended Data Fig. 5p, s–v) PubMed:30046111
Citrate synthase activity is a surrogate marker of total mitochondrial content/mass, and was similar across genotypes and brain regions (Figure 3i) suggesting that the defects in cellular respiration were due to altered mitochondrial quality, not content/mass PubMed:30126037
The release of epinephrine stimulates the body and causes a sudden release of glucose as well as an increase in blood pressure, respiration, and heart rate PubMed:28391535
This experiment demonstrated that under serum-free conditions, 4 hours of exposure to NaOH-dissolved heme induced complete deterioration of mitochondrial respiration at concentrations as low as 10 lmolL1, while exposure to albumin-associated heme in the presence of 2% FCS stimulated respiratory capacity to levels above baseline. PubMed:29610666
Exposure to HbFe41 resulted in a drop in hyperpolarized cell percentage over untreated control, thus indicating a significant mitochondrial depolarization or compromised mitochondrial respiration. PubMed:26974230
This experiment demonstrated that under serum-free conditions, 4 hours of exposure to NaOH-dissolved heme induced complete deterioration of mitochondrial respiration at concentrations as low as 10 lmolL1, while exposure to albumin-associated heme in the presence of 2% FCS stimulated respiratory capacity to levels above baseline. PubMed:29610666
Citrate synthase activity is a surrogate marker of total mitochondrial content/mass, and was similar across genotypes and brain regions (Figure 3i) suggesting that the defects in cellular respiration were due to altered mitochondrial quality, not content/mass PubMed:30126037
Exposure to HbFe41 resulted in a drop in hyperpolarized cell percentage over untreated control, thus indicating a significant mitochondrial depolarization or compromised mitochondrial respiration. PubMed:26974230
This experiment demonstrated that under serum-free conditions, 4 hours of exposure to NaOH-dissolved heme induced complete deterioration of mitochondrial respiration at concentrations as low as 10 lmolL1, while exposure to albumin-associated heme in the presence of 2% FCS stimulated respiratory capacity to levels above baseline. PubMed:29610666
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.