|
Separate |
a(HM:"stored erythrocytes") |
a(CHEBI:methemoglobin) |
p(MGI:Prdx2) |
|
Separate |
bp(MESH:"Platelet Activation") |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
|
Separate |
p(HGNC:HBB) |
bp(MESH:"Erythrocyte Deformability") |
bp(MESH:"Oxidative Stress") |
|
Separate |
a(CHEBI:heme) |
a(MESH:"Reactive Oxygen Species") |
bp(MESH:"Erythrocyte Deformability") |
|
Separate |
path(MESH:Inflammation) |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
|
Separate |
a(CHEBI:"carbon monoxide") |
a(CHEBI:heme) |
p(MGI:Hpx) |
|
Separate |
bp(MESH:"Erythrocyte Deformability") |
a(CHEBI:heme) |
p(MGI:Prdx2) |
|
Separate |
a(HM:"stored erythrocytes") |
a(CHEBI:heme) |
p(MGI:Prdx2) |
|
Separate |
a(CHEBI:"iron(2+)") |
a(CHEBI:lipopolysaccharide) |
p(MGI:Slc40a1) |
|
Separate |
path(MESH:"Vascular Diseases") |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
|
Separate |
p(MGI:Slc40a1) |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
|
Separate |
a(CHEBI:heme) |
p(HGNC:HP) |
path(MESH:"Pre-Eclampsia") |
|
Separate |
p(HGNC:ARG1) |
p(HGNC:HPX) |
path(MESH:Hemolysis) |
|
Separate |
a(HM:"stored erythrocytes") |
p(MGI:Prdx2) |
path(MESH:Hemolysis) |
|
Separate |
a(HM:"nitrite oxidation") |
a(CHEBI:heme) |
p(MGI:Prdx2) |
|
Separate |
p(PFAM:Proteasome) |
a(CHEBI:heme) |
bp(GO:"cellular homeostasis") |
|
Separate |
a(MESH:"haptoglobin-hemoglobin complex") |
p(HGNC:HP) |
path(MESH:"Pre-Eclampsia") |
|
Separate |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
complex(a(MESH:"Blood Transfusion"), p(MGI:Hpx)) |
|
Separate |
a(HM:"stored erythrocytes") |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
|
Separate |
a(CHEBI:heme) |
a(CHEBI:"carbon monoxide") |
path(HM:"vaso-occlusive crisis") |
|
Separate |
bp(GO:"inflammatory response") |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
|
Separate |
a(HM:"stored erythrocytes") |
bp(MESH:"Oxidative Stress") |
p(MGI:Prdx2) |
|
Separate |
path(MESH:Thrombosis) |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
|
Separate |
a(CHEBI:lactate) |
p(HGNC:HBB) |
p(HGNC:HP) |
|
Separate |
a(CHEBI:"carbon monoxide") |
a(CHEBI:antioxidant) |
a(CHEBI:heme) |
|
Separate |
a(CHEBI:heme) |
p(HGNC:HP) |
path(MESH:Thrombosis) |
|
Separate |
a(CHEBI:heme) |
bp(MESH:"Erythrocyte Deformability") |
bp(MESH:"Oxidative Stress") |
|
Separate |
a(CHEBI:heme) |
p(HGNC:HP) |
path(MESH:Hemolysis) |
|
Separate |
p(MGI:Cdc42) |
bp(MESH:Phagocytosis) |
p(MGI:Dock8) |
|
Separate |
a(CHEBI:heme) |
bp(MESH:"Erythrocyte Deformability") |
path(MESH:Thrombosis) |
|
Separate |
p(HGNC:HBB) |
bp(MESH:"Erythrocyte Deformability") |
path(MESH:Thrombosis) |
|
Separate |
a(HM:"nitrite oxidation") |
bp(MESH:"Oxidative Stress") |
p(MGI:Prdx2) |
|
Separate |
bp(MESH:"Oxidative Stress") |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
|
Mutual |
p(HGNC:HBB) |
p(HGNC:HP) |
path(HP:"Elevated mean arterial pressure") |
|
Mutual |
complex(a(CHEBI:"tin atom"), a(CHEBI:protoporphyrin)) |
p(MGI:Hp) |
p(MGI:Nfkb1) |
|
Mutual |
complex(a(CHEBI:"tin atom"), a(CHEBI:protoporphyrin)) |
p(MGI:Hpx) |
p(MGI:Nfkb1) |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Reactive Oxygen Species") |
p(HGNC:AMBP) |
|
Jens |
a(HM:erythrophagocytosis) |
p(HGNC:CD163) |
p(HGNC:HMOX1) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:HBB) |
path(MESH:"Vascular Diseases") |
|
Jens |
bp(GO:"inflammatory response") |
p(HGNC:IL1B) |
path(MESH:Inflammation) |
|
Jens |
bp(MESH:"Platelet Activation") |
p(HGNC:HBB) |
path(HP:"Paroxysmal nocturnal hemoglobinuria") |
|
Jens |
a(MESH:"Cell-Derived Microparticles") |
path(HM:"endothelial lesions") |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:ARG1) |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
path(MESH:"Acute Kidney Injury") |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
a(MESH:"Blood Transfusion") |
|
Jens |
a(CHEBI:"nitric oxide") |
a(CHEBI:heme) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:"iron(2+)") |
bp(MESH:"Oxidative Stress") |
p(HGNC:HBB) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:HP) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:heme) |
bp(MESH:"Platelet Activation") |
p(HGNC:SELP) |
|
Jens |
a(CHEBI:heme) |
bp(MESH:"Platelet Activation") |
p(HGNC:HBB) |
|
Jens |
a(MESH:ferrylhemoglobin) |
p(HGNC:CXCL8) |
path(MESH:Inflammation) |
|
Jens |
a(MESH:"Cell-Derived Microparticles") |
bp(MESH:Hemostasis) |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:F3) |
path(HM:"endothelial lesions") |
|
Jens |
p(HGNC:AMBP) |
p(HGNC:HBB) |
path(HM:"Oxidative damage") |
|
Jens |
p(MGI:Il1b) |
p(MGI:Nlrp3) |
p(MGI:P2rx4) |
|
Jens |
path(HP:"Paroxysmal nocturnal hemoglobinuria") |
path(MESH:Hemolysis) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
bp(MESH:"Platelet Activation") |
|
Jens |
a(CHEBI:methemoglobin) |
a(CHEBI:oxyhemoglobin) |
a(HM:"stored erythrocytes") |
|
Jens |
a(CHEBI:heme) |
bp(GO:"inflammatory response") |
p(HGNC:IL1B) |
|
Jens |
bp(MESH:"Platelet Aggregation") |
p(HGNC:HBB) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Reactive Oxygen Species") |
path(MESH:Thrombosis) |
|
Jens |
a(MESH:"Erythrocytes, Abnormal") |
p(HGNC:HBB) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(MESH:"Reactive Oxygen Species") |
path(MESH:Thrombosis) |
|
Jens |
path(HP:"Hemolytic-uremic syndrome") |
path(MESH:Hemolysis) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
bp(GO:"protein oxidation") |
bp(MESH:"Oxidative Stress") |
|
Jens |
a(CHEBI:heme) |
p(HGNC:TNF) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:HP) |
path(MESH:"Anemia, Sickle Cell") |
|
Jens |
a(CHEBI:heme) |
bp(GO:vasoconstriction) |
p(HGNC:HBB) |
|
Jens |
complex(a(MESH:"Blood Transfusion"), p(MGI:Hpx)) |
p(MGI:Hmox1) |
p(MGI:Hpx) |
|
Jens |
a(CHEBI:"iron trichloride") |
p(HGNC:HBB) |
path(HM:"Endothelial dysfunction") |
|
Jens |
a(CHEBI:methemoglobin) |
a(MESH:"Blood Transfusion") |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
p(MGI:Hpx) |
p(MGI:Tfrc) |
|
Jens |
a(CHEBI:heme) |
a(MESH:Cytokines) |
p(HGNC:AMBP) |
|
Jens |
a(CHEBI:heme) |
a(HM:"stored erythrocytes") |
bp(MESH:"Bacterial Load") |
|
Jens |
a(CHEBI:heme) |
a(HM:"oxidative reactions") |
p(HGNC:HP) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(HM:"stored erythrocytes") |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(HM:"stored erythrocytes") |
p(HGNC:HBB) |
|
Jens |
a(CHEBI:heme) |
path(MESH:"Vascular System Injuries") |
path(MESH:Hemolysis) |
|
Jens |
p(MGI:Il1b) |
p(MGI:Nlrp3) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:heme) |
p(MGI:Casp1) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:CD55) |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:heme) |
path(MESH:"Thrombotic Microangiopathies") |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:HPX) |
p(HGNC:IL10) |
|
Jens |
a(CHEBI:"nitric oxide") |
a(HM:"stored erythrocytes") |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(MESH:"Reactive Oxygen Species") |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:"carbon monoxide") |
a(CHEBI:heme) |
bp(GO:"inflammatory response") |
|
Jens |
a(CHEBI:"nitric oxide") |
p(HGNC:HBB) |
path(MESH:"Platelet Aggregation") |
|
Jens |
a(HM:"stored erythrocytes") |
p(HGNC:HBB) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:heme) |
a(MESH:Cytokines) |
bp(MESH:"Platelet Activation") |
|
Jens |
a(CHEBI:heme) |
path(HM:"endothelial lesions") |
path(MESH:Thrombosis) |
|
Jens |
p(HGNC:HBB) |
path(HP:"Paroxysmal nocturnal hemoglobinuria") |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:TNF) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:HBB) |
path(HM:"endothelial lesions") |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Reactive Oxygen Species") |
path(MESH:"Reperfusion Injury") |
|
Jens |
a(CHEBI:heme) |
p(MGI:Il1b) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:AMBP) |
p(HGNC:HBB) |
|
Jens |
a(CHEBI:"nitric oxide") |
path(MESH:Hemolysis) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:"iron(2+)") |
p(HGNC:HBB) |
path(MESH:"Vascular Diseases") |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:"nitric oxide") |
a(MESH:"Cell Adhesion Molecules") |
|
Jens |
a(CHEBI:heme) |
bp(MESH:"Oxidative Stress") |
p(HGNC:HBB) |
|
Jens |
a(CHEBI:"carbon monoxide") |
a(CHEBI:heme) |
p(MGI:Hpx) |
|
Jens |
a(CHEBI:"lipid hydroperoxide") |
a(HM:"Erythrocytes, lysed") |
bp(HM:"Atheromatous lesions") |
|
Jens |
a(CHEBI:"iron(2+)") |
a(MESH:"Reactive Oxygen Species") |
p(MGI:Slc40a1) |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Reactive Oxygen Species") |
path(MESH:Inflammation) |
|
Jens |
a(MESH:"Cell-Derived Microparticles") |
path(HP:Hypercoagulability) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:"iron(2+)") |
p(HGNC:HBB) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(MESH:"Blood Transfusion") |
p(HGNC:HBB) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(HM:"stored erythrocytes") |
bp(MESH:"Oxidative Stress") |
|
Jens |
a(MESH:"Reactive Oxygen Species") |
bp(GO:"inflammatory response") |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
path(MESH:"Vascular Diseases") |
|
Jens |
p(HGNC:HBB) |
path(MESH:"Vascular Diseases") |
path(MESH:Hemolysis) |
|
Jens |
bp(MESH:"Oxidative Stress") |
p(HGNC:AMBP) |
p(HGNC:HBB) |
|
Jens |
a(CHEBI:"iron(2+)") |
bp(MESH:"Platelet Activation") |
p(HGNC:HBB) |
|
Jens |
p(HGNC:ARG1) |
path(MESH:"Pulmonary Embolism") |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Reactive Oxygen Species") |
p(MGI:Slc40a1) |
|
Jens |
a(CHEBI:heme) |
p(MGI:Hmox1) |
p(MGI:Sqstm1) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
p(MGI:Slc40a1) |
|
Jens |
a(CHEBI:"desferrioxamine B") |
p(HGNC:HBB) |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
bp(GO:"inflammatory response") |
bp(HM:"macrophage M1 polarization") |
|
Jens |
a(CHEBI:"carbon monoxide") |
a(CHEBI:heme) |
p(MGI:Hmox1) |
|
Jens |
a(CHEBI:heme) |
a(MESH:Cytokines) |
p(HGNC:TLR9) |
|
Jens |
a(CHEBI:"hydrogen peroxide") |
a(CHEBI:heme) |
a(CHEBI:methemoglobin) |
|
Jens |
a(MESH:"Cell-Derived Microparticles") |
bp(GO:"complement activation") |
bp(MESH:Eryptosis) |
|
Jens |
a(CHEBI:"phosphatidyl-L-serine") |
path(MESH:Hemolysis) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
a(MESH:ferrylhemoglobin) |
path(MESH:Inflammation) |
|
Jens |
path(MESH:"Pulmonary Embolism") |
path(MESH:"beta-Thalassemia") |
path(MESH:Hemolysis) |
|
Jens |
a(MESH:"Cell-Derived Microparticles") |
path(HP:"Paroxysmal nocturnal hemoglobinuria") |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:Thrombin) |
path(MESH:"Disseminated Intravascular Coagulation") |
path(MESH:Hemolysis) |
|
Jens |
a(HM:erythrophagocytosis) |
p(HGNC:CD163) |
path(MESH:Hematoma) |
|
Jens |
a(CHEBI:heme) |
path(MESH:"Vascular Diseases") |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
path(MESH:Hemolysis) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:heme) |
path(HM:"endothelial lesions") |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
a(MESH:Cytokines) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(MESH:"Reactive Oxygen Species") |
bp(MESH:"Cytotoxicity, Immunologic") |
|
Jens |
a(MESH:"Reactive Oxygen Species") |
a(MESH:Cytokines) |
p(HGNC:AMBP) |
|
Jens |
a(CHEBI:heme) |
p(MGI:Il1b) |
p(MGI:P2rx4) |
|
Jens |
a(MESH:"haptoglobin-hemoglobin complex") |
p(HGNC:CD163) |
path(MESH:"Pre-Eclampsia") |
|
Jens |
a(HM:"ABO-incompatible erythrocytes") |
path(MESH:"Transfusion Reaction") |
path(MESH:Death) |
|
Jens |
a(CHEBI:"nitric oxide") |
bp(MESH:"Platelet Aggregation") |
p(HGNC:HBB) |
|
Jens |
p(HGNC:HBB) |
path(HP:"Paroxysmal nocturnal hemoglobinuria") |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:methemoglobin) |
p(HGNC:HBB) |
path(MESH:Hemolysis) |
|
Jens |
a(MESH:"Cell-Derived Microparticles") |
bp(GO:"complement activation") |
path(MESH:Inflammation) |
|
Jens |
p(HGNC:HBB) |
path(MESH:"Anemia, Sickle Cell") |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
path(MESH:"Thrombotic Microangiopathies") |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
a(MESH:"Cell Adhesion Molecules") |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Complement Membrane Attack Complex") |
path(MESH:Hemolysis) |
|
Jens |
a(HM:"stored erythrocytes") |
bp(MESH:"Oxidative Stress") |
p(HGNC:HBB) |
|
Jens |
a(CHEBI:"iron(2+)") |
bp(GO:"inflammatory response") |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:"4-hydroxynon-2-enal") |
a(MESH:"Blood Transfusion") |
p(HGNC:HP) |
|
Jens |
a(HM:"stored erythrocytes") |
bp(MESH:"Erythrocyte Deformability") |
p(MGI:Prdx2) |
|
Jens |
a(MESH:"Reactive Oxygen Species") |
bp(MESH:"Oxidative Stress") |
p(HGNC:AMBP) |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Cell Adhesion Molecules") |
p(HGNC:HMOX1) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:HBB) |
path(HM:"vaso-occlusive crisis") |
|
Jens |
a(CHEBI:heme) |
p(HGNC:IL1B) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:"nitric oxide") |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Blood Transfusion") |
p(HGNC:HP) |
|
Jens |
a(CHEBI:heme) |
p(MGI:Hmox1) |
p(MGI:Hspa2) |
|
Jens |
a(CHEBI:ATP) |
a(CHEBI:heme) |
p(HGNC:HPX) |
|
Jens |
a(CHEBI:heme) |
path(MESH:Hemolysis) |
path(MESH:Malaria) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:HBB) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:heme) |
p(MGI:Il1b) |
p(MGI:P2rx7) |
|
Jens |
p(HGNC:HBB) |
path(HM:"Endothelial dysfunction") |
path(MESH:Thrombosis) |
|
Jens |
a(MESH:"Adenosine Diphosphate") |
bp(MESH:"Platelet Activation") |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
p(MGI:Hmox1) |
p(PFAM:ubiquitin) |
|
Jens |
a(CHEBI:heme) |
a(HM:"oxidative reactions") |
p(HGNC:HBB) |
|
Jens |
a(CHEBI:heme) |
bp(MESH:"Oxidative Stress") |
p(MGI:Hmox1) |
|
Jens |
a(CHEBI:methemoglobin) |
a(HM:"stored erythrocytes") |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:"nitric oxide") |
a(CHEBI:heme) |
a(MESH:"Cell Adhesion Molecules") |
|
Jens |
a(MESH:"Cell-Derived Microparticles") |
bp(MESH:Hemostasis) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:HPX) |
p(HGNC:MRC1) |
|
Jens |
p(MGI:Casp1) |
p(MGI:Il1b) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:"nitric oxide") |
bp(MESH:"Platelet Activation") |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
a(MESH:"Reactive Oxygen Species") |
|
Jens |
a(CHEBI:heme) |
a(HM:"stored erythrocytes") |
p(HGNC:HBB) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(MESH:"Blood Transfusion") |
bp(MESH:"Platelet Activation") |
|
Jens |
a(CHEBI:heme) |
bp(MESH:"Erythrocyte Count") |
bp(MESH:"Erythrocyte Deformability") |
|
Jens |
p(HGNC:AMBP) |
path(HM:"Oxidative damage") |
path(MESH:Hemorrhage) |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Reactive Oxygen Species") |
bp(GO:"endothelial cell activation") |
|
Jens |
a(CHEBI:heme) |
p(HGNC:AMBP) |
path(MESH:"Pre-Eclampsia") |
|
Jens |
a(CHEBI:heme) |
p(HGNC:HBB) |
path(MESH:"Anemia, Sickle Cell") |
|
Jens |
a(CHEBI:"oxidised LDL") |
a(CHEBI:heme) |
p(HGNC:HMOX1) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
bp(HM:"macrophage M1 polarization") |
|
Jens |
a(CHEBI:heme) |
bp(GO:"inflammatory response") |
path(MESH:"Knee Injuries") |
|
Jens |
a(CHEBI:heme) |
path(MESH:Hemolysis) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Reactive Oxygen Species") |
bp(MESH:"Oxidative Stress") |
|
Jens |
a(CHEBI:heme) |
bp(GO:"complement activation") |
path(MESH:Hemolysis) |
|
Jens |
p(HGNC:HBB) |
path(MESH:Hemolysis) |
path(MESH:Thrombophilia) |
|
Jens |
a(HM:"fibrin deposition") |
a(MESH:"Extracellular Traps") |
path(MESH:Hemolysis) |
|
Jens |
p(HGNC:CD59, var("p.Cys89Tyr")) |
p(HGNC:HBB) |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:"iron(2+)") |
complex(a(MESH:"Blood Transfusion"), p(MGI:Hp)) |
p(HGNC:HBB) |
|
Jens |
a(CHEBI:"iron(2+)") |
p(MGI:Slc40a1) |
path(MESH:"Porphyria, Erythropoietic") |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Reactive Oxygen Species") |
bp(MESH:Apoptosis) |
|
Jens |
a(CHEBI:heme) |
a(CHEBI:methemoglobin) |
a(HM:"stored erythrocytes") |
|
Jens |
a(CHEBI:heme) |
p(HGNC:CXCL8) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
a(HM:"nitrite oxidation") |
bp(MESH:"Oxidative Stress") |
|
Jens |
a(CHEBI:"iron(2+)") |
a(MESH:"Reactive Oxygen Species") |
bp(MESH:"Oxidative Stress") |
|
Jens |
a(CHEBI:heme) |
p(HGNC:AMBP) |
path(HM:"Oxidative damage") |
|
Jens |
a(CHEBI:heme) |
a(CHEBI:methemoglobin) |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:"nitric oxide") |
bp(MESH:"Erythrocyte Aggregation") |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:"phosphatidyl-L-serine") |
a(HM:"stored erythrocytes") |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
p(MGI:Il1b) |
p(MGI:Nlrp3) |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Reactive Oxygen Species") |
a(MESH:Cytokines) |
|
Jens |
a(CHEBI:heme) |
a(HM:"stored erythrocytes") |
path(MESH:Inflammation) |
|
Jens |
a(MESH:"Cell-Derived Microparticles") |
path(MESH:Hemolysis) |
path(MESH:Thrombosis) |
|
Jens |
p(HGNC:CD59, var("p.Cys89Tyr")) |
p(HGNC:HBB) |
path(MESH:Thrombosis) |
|
Jens |
bp(GO:"complement activation") |
path(MESH:Hemolysis) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:"nitric oxide") |
a(CHEBI:heme) |
bp(GO:"endothelial cell activation") |
|
Jens |
a(CHEBI:heme) |
a(HM:"stored erythrocytes") |
bp(MESH:"Erythrocyte Deformability") |
|
Jens |
a(CHEBI:"hydrogen peroxide") |
a(CHEBI:heme) |
bp(MESH:"Oxidative Stress") |
|
Jens |
a(MESH:"Cell-Derived Microparticles") |
bp(GO:"complement activation") |
path(MESH:Hemolysis) |
|
Jens |
a(HM:erythrophagocytosis) |
p(HGNC:HMOX1) |
path(MESH:Hematoma) |
|
Jens |
a(CHEBI:"iron(2+)") |
p(HGNC:HBB) |
path(MESH:Thrombosis) |
|
Jens |
bp(MESH:"Platelet Activation") |
path(HP:"Paroxysmal nocturnal hemoglobinuria") |
path(MESH:Thrombosis) |
|
Jens |
a(HM:"stored erythrocytes") |
path(MESH:Hemolysis) |
path(MESH:Inflammation) |
|
Jens |
p(HGNC:TNF) |
path(MESH:Hemolysis) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
a(HM:"stored erythrocytes") |
|
Jens |
a(CHEBI:heme) |
a(HM:"stored erythrocytes") |
p(MGI:Hmgb1) |
|
Jens |
a(CHEBI:"nitric oxide") |
p(HGNC:HBB) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(MESH:"Reactive Oxygen Species") |
bp(MESH:"Platelet Activation") |
|
Jens |
p(HGNC:HBB) |
path(HM:"endothelial lesions") |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:"phosphatidyl-L-serine") |
a(CHEBI:Thrombin) |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Reactive Oxygen Species") |
bp(MESH:"Platelet Activation") |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Reactive Oxygen Species") |
bp(GO:"inflammatory response") |
|
Jens |
a(HM:"stored erythrocytes") |
bp(MESH:"Oxidative Stress") |
p(MGI:Prdx2) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
bp(GO:"inflammatory response") |
|
Jens |
a(CHEBI:heme) |
p(HGNC:HBB) |
path(MESH:"Vascular System Injuries") |
|
Jens |
a(HM:"stored erythrocytes") |
bp(MESH:"Erythrocyte Deformability") |
p(HGNC:HBB) |
|
Jens |
a(CHEBI:"carbon monoxide") |
a(CHEBI:heme) |
bp(MESH:Vasodilation) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(MESH:"Reactive Oxygen Species") |
bp(GO:"inflammatory response") |
|
Jens |
a(CHEBI:"carbon monoxide") |
a(CHEBI:heme) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:HBB) |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
p(MGI:Bach1) |
p(MGI:Spic) |
|
Jens |
a(CHEBI:lactate) |
p(HGNC:HBB) |
p(HGNC:HP) |
|
Jens |
a(MESH:"Complement Membrane Attack Complex") |
p(HGNC:CD59, var("p.Cys89Tyr")) |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:"nitric oxide") |
complex(p(HGNC:F13A1), p(HGNC:F13B)) |
path(MESH:"Clot Retraction") |
|
Jens |
a(CHEBI:"nitric oxide") |
p(HGNC:HBB) |
path(MESH:Thrombosis) |
|
Jens |
p(HGNC:TNF) |
path(MESH:Hemolysis) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
path(MESH:"Anemia, Sickle Cell") |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
a(MESH:Cytokines) |
p(HGNC:TLR2) |
|
Jens |
a(MESH:"Cell-Derived Microparticles") |
bp(MESH:"Platelet Activation") |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Complement C3a") |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:"carbon monoxide") |
a(CHEBI:antioxidant) |
a(CHEBI:heme) |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Complement C5a") |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:methemoglobin) |
a(HM:"stored erythrocytes") |
p(HGNC:HBB) |
|
Jens |
a(HM:"Glucose-6-phosphate dehydrogenase deficiency") |
path(MESH:Hemolysis) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:"iron trichloride") |
p(HGNC:HBB) |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:ARG1) |
p(HGNC:HPX) |
|
Jens |
p(MGI:Il1b) |
p(MGI:Nlrp3) |
p(MGI:P2rx7) |
|
Jens |
a(CHEBI:"nitric oxide") |
path(MESH:Hemolysis) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
bp(GO:"complement activation") |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:HMOX1) |
path(MESH:Atherosclerosis) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:VWF) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:"nitric oxide") |
a(CHEBI:heme) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:"iron trichloride") |
p(HGNC:HBB) |
path(MESH:"Vascular System Injuries") |
|
Jens |
a(CHEBI:"nitric oxide") |
a(CHEBI:heme) |
bp(MESH:"Platelet Aggregation") |
|
Jens |
a(CHEBI:"nitric oxide") |
a(CHEBI:heme) |
bp(MESH:"Platelet Activation") |
|
Jens |
a(MESH:"Blood Transfusion") |
p(HGNC:HBB) |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:CXCL8) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:"phosphatidyl-L-serine") |
path(HP:Hypercoagulability) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:"nitric oxide") |
a(CHEBI:"phosphatidyl-L-serine") |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
bp(MESH:"Platelet Aggregation") |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
a(HM:"stored erythrocytes") |
path(MESH:Hemolysis) |
|
Jens |
path(MESH:"Disseminated Intravascular Coagulation") |
path(MESH:Hemolysis) |
path(MESH:Thrombosis) |
|
Jens |
bp(MESH:Hemostasis) |
path(MESH:Hemolysis) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
bp(MESH:"Oxidative Stress") |
p(HGNC:AMBP) |
|
Jens |
a(CHEBI:"iron(2+)") |
bp(MESH:"Platelet Activation") |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
p(MGI:Hmox1) |
path(MESH:Inflammation) |
|
Jens |
bp(MESH:"Platelet Activation") |
p(HGNC:HBB) |
path(MESH:Thrombosis) |
|
Jens |
a(MESH:"Blood Transfusion") |
p(HGNC:HBB) |
p(HGNC:HP) |
|
Jens |
a(CHEBI:heme) |
bp(MESH:"Platelet Activation") |
path(MESH:Thrombosis) |
|
Jens |
p(HGNC:HBB) |
p(HGNC:HP) |
path(MESH:"Anemia, Sickle Cell") |
|
Jens |
a(CHEBI:"carbon monoxide") |
a(CHEBI:heme) |
bp(GO:"cell proliferation") |
|
Jens |
bp(MESH:"Erythrocyte Volume") |
bp(MESH:Hemostasis) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
bp(MESH:"Lipid Peroxidation") |
p(HGNC:HP) |
|
Jens |
a(CHEBI:heme) |
p(MGI:Nlrp3) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:heme) |
a(MESH:Cytokines) |
p(HGNC:NOD1) |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Reactive Oxygen Species") |
path(MESH:Atherosclerosis) |
|
Jens |
a(CHEBI:heme) |
p(MGI:Nlrp3) |
p(MGI:P2rx7) |
|
Jens |
a(CHEBI:heme) |
bp(GO:"inflammatory response") |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:heme) |
a(HM:"stored erythrocytes") |
bp(MESH:"Oxidative Stress") |
|
Jens |
a(MESH:"Cell-Derived Microparticles") |
p(HGNC:VWF) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:HBB) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
bp(MESH:"Erythrocyte Deformability") |
p(HGNC:HBB) |
|
Jens |
a(CHEBI:"lead nitrate") |
path(MESH:"Hematopoiesis, Extramedullary") |
path(MESH:Anemia) |
|
Jens |
a(CHEBI:"hydrogen peroxide") |
a(CHEBI:methemoglobin) |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
a(MESH:"Blood Transfusion") |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
a(MESH:Cytokines) |
p(HGNC:NFKB1) |
|
Jens |
p(HGNC:HBB) |
path(MESH:Hemolysis) |
path(MESH:Inflammation) |
|
Jens |
a(CHEBI:heme) |
p(HGNC:IL1B) |
path(MESH:Inflammation) |
|
Jens |
p(HGNC:HBB) |
path(HM:"endothelial lesions") |
path(MESH:Hemolysis) |
|
Jens |
p(HGNC:CD163) |
p(HGNC:HMOX1) |
path(MESH:Hematoma) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:lipopolysaccharide) |
p(HGNC:HBB) |
|
Jens |
a(CHEBI:methemoglobin) |
a(MESH:"Blood Transfusion") |
p(HGNC:HBB) |
|
Jens |
a(MESH:"Blood Transfusion") |
bp(MESH:"Platelet Activation") |
p(HGNC:HBB) |
|
Jens |
a(CHEBI:"nitric oxide") |
bp(MESH:"Platelet Activation") |
p(HGNC:HBB) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:"nitric oxide") |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
bp(GO:vasoconstriction) |
path(MESH:Hemolysis) |
|
Jens |
p(HGNC:HBB) |
p(HGNC:HP) |
path(HP:"Paroxysmal nocturnal hemoglobinuria") |
|
Jens |
a(CHEBI:"L-arginine") |
bp(MESH:"Platelet Aggregation") |
p(HGNC:HBB) |
|
Jens |
p(HGNC:CD59, var("p.Cys89Tyr")) |
path(HP:Hypercoagulability) |
path(MESH:Thrombosis) |
|
Jens |
p(HGNC:HBB) |
path(MESH:Hemolysis) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:"iron(2+)") |
bp(GO:"inflammatory response") |
bp(HM:"macrophage M1 polarization") |
|
Jens |
path(MESH:"Thrombotic Microangiopathies") |
path(MESH:Hemolysis) |
path(MESH:Thrombosis) |
|
Jens |
bp(HM:"Atheromatous lesions") |
p(HGNC:HMOX1) |
path(MESH:Hematoma) |
|
Jens |
a(CHEBI:heme) |
bp(MESH:"Erythrocyte Deformability") |
path(MESH:Thrombosis) |
|
Jens |
bp(MESH:"Erythrocyte Deformability") |
p(HGNC:HBB) |
path(MESH:Thrombosis) |
|
Jens |
a(MESH:"Cell-Derived Microparticles") |
path(MESH:Hemolysis) |
path(MESH:Thrombophilia) |
|
Jens |
a(HM:"nitrite oxidation") |
bp(MESH:"Oxidative Stress") |
p(MGI:Prdx2) |
|
Jens |
a(CHEBI:heme) |
path(MESH:"beta-Thalassemia") |
path(MESH:Hemolysis) |
|
Jens |
p(HGNC:HBB) |
path(MESH:"Vascular System Injuries") |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:"lead nitrate") |
a(MESH:Reticulocytes) |
bp(MESH:Erythropoiesis) |
|
Jens |
a(HM:"stored erythrocytes") |
p(HGNC:HBB) |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:"lead nitrate") |
a(CHEBI:heme) |
|
Jens |
a(CHEBI:"nitric oxide") |
bp(GO:"endothelial cell activation") |
p(HGNC:HBB) |
|
Jens |
p(HGNC:AMBP) |
path(MESH:"Knee Injuries") |
path(MESH:"Osteoarthritis, Knee") |
|
Jens |
a(MESH:"Cell-Derived Microparticles") |
p(HGNC:CD59, var("p.Cys89Tyr")) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:"iron trichloride") |
path(MESH:"Vascular System Injuries") |
path(MESH:Hemolysis) |
|
Jens |
a(CHEBI:heme) |
bp(GO:"necroptotic process") |
p(HGNC:HMOX1) |
|
Jens |
bp(GO:vasoconstriction) |
p(HGNC:HBB) |
path(MESH:Hemolysis) |
|
Jens |
a(MESH:"Erythrocytes, Abnormal") |
bp(MESH:"Oxidative Stress") |
p(HGNC:HBB) |
|
Jens |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
bp(MESH:"Oxidative Stress") |
|
Jens |
a(CHEBI:heme) |
p(MGI:Nlrp3) |
p(MGI:P2rx4) |
|
Jens |
a(CHEBI:heme) |
path(HM:"Endothelial dysfunction") |
path(MESH:Thrombosis) |
|
Jens |
p(HGNC:CD59, var("p.Cys89Tyr")) |
path(MESH:Hemolysis) |
path(MESH:Thrombosis) |
|
Jens |
a(CHEBI:heme) |
bp(GO:"inflammatory response") |
p(HGNC:TLR4) |
|
Jens |
a(CHEBI:"hydrogen peroxide") |
a(CHEBI:heme) |
path(MESH:Hemolysis) |
|
Jens |
a(MESH:"Cell-Derived Microparticles") |
path(HM:"endothelial lesions") |
path(MESH:Hemolysis) |
|
Increase Mismatch |
a(CHEBI:heme) |
path(MESH:"Acute Kidney Injury") |
p(MGI:Hmox1) |
|
Increase Mismatch |
a(CHEBI:heme) |
p(MGI:Hmox1) |
path(MESH:"Vascular System Injuries") |
|
Increase Mismatch |
a(CHEBI:heme) |
p(MGI:Hmox1) |
p(MGI:Il1b) |
|
Increase Mismatch |
a(CHEBI:heme) |
p(MGI:Hmox1) |
path(HM:"vaso-occlusive crisis") |
|
Increase Mismatch |
a(CHEBI:heme) |
p(HGNC:HMOX1) |
path(MESH:Atherosclerosis) |
|
Increase Mismatch |
a(CHEBI:methemoglobin) |
a(CHEBI:heme) |
p(MGI:Hmox1) |
|
Increase Mismatch |
a(CHEBI:protoporphyrin) |
p(MGI:Hmox1) |
p(MGI:Il1b) |
|
Increase Mismatch |
a(MESH:"Blood Transfusion") |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
|
Increase Mismatch |
a(MESH:ferrylhemoglobin) |
a(CHEBI:heme) |
p(MGI:Hmox1) |
|
Increase Mismatch |
p(HGNC:HBB) |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
|
Increase Mismatch |
p(HGNC:HBB) |
a(CHEBI:heme) |
p(MGI:Hmox1) |
|
Increase Mismatch |
p(HGNC:HBB) |
p(MGI:Hmox1) |
path(MESH:"Vascular System Injuries") |
|
Decrease Mismatch |
a(MESH:"haptoglobin-hemoglobin complex") |
p(HGNC:HP) |
p(HGNC:HBB) |
|
Decrease Mismatch |
p(MGI:Hpx) |
a(CHEBI:heme) |
p(MGI:Hmox1) |
|
Decrease Mismatch |
p(MGI:Hpx) |
p(MGI:Hmox1) |
path(HM:"vaso-occlusive crisis") |
|
Decrease Mismatch |
p(MGI:Hp) |
path(MESH:"Acute Kidney Injury") |
p(MGI:Hmox1) |
|
Decrease Mismatch |
p(MGI:Hp) |
path(HM:"vaso-occlusive crisis") |
p(MGI:Hmox1) |
|
Decrease Mismatch |
p(HGNC:AMBP) |
bp(MESH:Phagocytosis) |
a(CHEBI:heme) |
|
Decrease Mismatch |
p(HGNC:FTH1) |
a(CHEBI:"iron(2+)") |
a(CHEBI:heme) |
|
Decrease Mismatch |
p(MGI:Hmox1) |
p(MGI:Sqstm1) |
a(CHEBI:heme) |